1. After a single IV dose of 1000mg of a drug, the following concentrations were obtained: a. Calculate A,,B, b. Write down the best fit equation that represents the concentration time data c. Calculate the concentration of the drug at 24 hours after dosing d. Calculate Vc,AUC and CLT 3. A drug that follows a two compartment pharmacokinetic model was given as a single IV bolus dose of 5.6mg/kg to a healthy 90kg volunteer. The equation that describes the plasma concentration-time profile is: Cp=18e2.8t+6e0.11t (Conc. In mg/L and time in hours) a. Calculate Vc,Vb,AUC,CLT,k1,k2,k3. b. Write the equation if the dose given is 11.2mg/kg. 1. After a single IV dose of 1000mg of a drug, the following concentrations were obtained: a. Calculate A,,B, b. Write down the best fit equation that represents the concentration time data c. Calculate the concentration of the drug at 24 hours after dosing d. Calculate Vc,AUC and CLT 3. A drug that follows a two compartment pharmacokinetic model was given as a single IV bolus dose of 5.6mg/kg to a healthy 90kg volunteer. The equation that describes the plasma concentration-time profile is: Cp=18e2.8t+6e0.11t (Conc. In mg/L and time in hours) a. Calculate Vc,Vb,AUC,CLT,k1,k2,k3. b. Write the equation if the dose given is 11.2mg/kg