1. AIDS-related risk factor. A national study of AIDS risk factors used a random-digit dialing technique to contact study participants. Among the 2673 hetero-sexual adults in the sample, 170 reported two or more sexual partners in the past 12 months.

Use "+4 method"

n-tilda = ?

p-tilda = ?

Partners-tilda = ?

Standard Error = ?

90$ confidence interval

z = 1.645

Po = p-tilda +/- (Z* x SE)

LCL = ?

UCL = ?

2. BRCA1 mutations in familial breast cancer cases. Of 169 women having breast cancer and a familial risk factor, 27 had an inherited BRCA1 mutation. Based on this information, estimate the prevalence of BRCA1 mutation in women with familial breast cancer. Include a 95% confidence interval for the prevalence.

use "+4 method"

n-tilda = ?

p-tilda = ?

BRCA-tilda = ?

Standard Error = ?

95% confidence interval

Z = 1.96

Po = p-tilda+/-(Z* x SE)

LCL = ?

UCL = ?