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1. Choose one: In a nucleophilic acyl substitution reaction... (1 point) a. protonation of the carbonyl is followed immediately by loss of the leaving group.

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1. Choose one: In a nucleophilic acyl substitution reaction... (1 point) a. protonation of the carbonyl is followed immediately by loss of the leaving group. b. loss of the leaving group is followed by rearrangement of the carbocation. c. addition to the carbonyl by a nucleophile is followed by loss of the leaving group. d. the attacking nucleophile must be a weaker base than the leaving group. e. an S+2 reaction occurs. 2. Which of the following conditions will drive the equilibrium of the Fischer esterification toward ester formation? Choose all that apply. (1 point) a. addition of excess water b addition of excess alcohol c removal of water as it is formed d. addition of an inorganic acid as a catalyst

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