1. Place 25 Red (S) and 25 Blue (s) beads into the 100 ml beaker and mix well.

2. Randomly (without looking) remove 2 beads. Repeat 10 times (without returning the beads

to the beaker), each timme recording if it was a SS, Ss or ss.

3. Remove each ss from the population they died.

4. The remaining beads survived and reproduced.

5. Count how many red and blue beads remained (separately) and place twice that number

back in the beaker.

6. Repeat the process 7 times

Quesitons:

1. What is the remaining ratio of alleles?

2. Have any been selected against?

3. Given enough generations, would you expect one of these alleles to completely disappear

from the population? Why or why not?

4. Would this be different if you started with a larger population? Smaller?

5. After hundreds or even thousands of generations both alleles are still common in those

of African Ancestry. How would you explain this?

6. The worldwide distribution of sickle gene matches very closely to the worldwide distribution of Malaria.

Is this significant? Why or why not?