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12. Anesthetic drug action is thought to involve the solubility of the anesthetic in the hydrocarbon region of the lipid bilayer of biological membranes. According

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12. Anesthetic drug action is thought to involve the solubility of the anesthetic in the hydrocarbon region of the lipid bilayer of biological membranes. According to the Meyer- Overton hypothesis, anesthesia occurs whenever the concentration of drug is greater than 0.03 mol/kg membrane, no matter what the anesthetic. a. For gaseous anesthetics like nitrous oxide or ether, use Henry's law and write the appropriate formula that would help you determine what gas pressure of anesthetic to use in the inhalation mix for a patient in order to achieve the desired membrane concentration. (1.5 points) b. Lipid bilayers 'melt from a solid-like state to a liquid-like state. Will the introduction of the anesthetic lead to an increase, decrease, or no change to the melting temperature? If the melting temperature changes, how would you predict the change? (1.5 points)

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