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7. Two missense mutations in the gene that encodes an enzyme called superoxide dismutase cause amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease). This
7. Two missense mutations in the gene that encodes an enzyme called superoxide dismutase cause amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease). This disorder causes loss of neurological function over a 5-year period. One mutation alters the amino acid asparagine (Asn) to lysine (Lys). The other changes an isoleucine (Ille) to a threonine (Thr). List the codons involved and describe how single-base mutations alter the amino acids they specify.
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Fundamentals of biochemistry Life at the Molecular Level
Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt
4th edition
470547847, 978-0470547847
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