1.Based on the article's headline, toxicologist agrees with the need for a critical review of the current occupational exposure limit (OEL) in the industry settings to protect workers in the pharmaceutical industry. Received: 12 March 2021 Revised: 26 June 2021 Accepted: 26 June 2021 DOI: 10.1002/jat.4218 Journal of REVIEW ARTICLE AppliedToxicology WILEY Approaches for setting occupational exposure limits in the pharmaceutical industry Varun Ahuja | Mohan Krishnappa Safety Assessment Department, Syngene International Limited, Bangalore, India Abstract The use of pharmaceutical drugs has provided a cure for many diseases. However, Correspondence Varun Ahuja, PHD, DABT, ERT, unintended exposure to drugs in the manufacturing workplace can cause significant Lead Toxicologist, Safety Assessment health hazards to workers. It is important to protect the workforce from these delete- Department, Syngene International Limited, Biocon Park, SEZ, Bommasandra-Jigani Link rious effects by limiting exposure to an acceptable level, the occupational exposure Road, Bangalore 560099, India. limit (OEL). OEL is defined as airborne concentrations (expressed as a time-weighted Email: varun.ahuja@syngeneintl.com. average for a conventional 8-h workday and a 40-h work week) of a substance to which nearly all workers may be repeatedly exposed (for a working lifetime) without (a)Identify THREE (3) possible biological or chemical hazards exposed to the workers in the pharmaceutical manufacturers. (b) Describe TWO (2) main challenges in setting a new airborne concentration of a substance for the workers in the pharmaceutical manufacturers. (c) Explain the role of OSHA 1994 in supporting the management of biological or chemicals in pharmaceutical manufacturers