2. An 84 kg University of Toledo groundskeeper who is spraying a 100 mg/L solution of the insecticide dieldrin (MW = 381; logP = 4.56) on some trees exposes 100 cm 2 of his skin to the solution over a 4 hr period. Dieldrin has a half-life of about 6 months, a volume of distribution of about 40 L/kg, and a dermal permeability of about 3 x 10-6 cm/sec.

(a) Estimate the absorption rate during the exposure period assuming the blood concentration is much lower than the skin concentration (i.e., take the blood level to be zero in the skin absorption equation). (5 points)