Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

2. Bladder Cancer Data. An exercise in the book Pagano and Gauvreau (2000) 2 features data on 86 patients who after surgery were assigned to

image text in transcribed
image text in transcribed
2. Bladder Cancer Data. An exercise in the book Pagano and Gauvreau (2000) 2 features data on 86 patients who after surgery were assigned to placebo or chemotherapy (thiopeta). Endpoint was the time to cancer recurrence (in months). Variables are: time, group (0 - placebo, 1- chemotherapy), and observed (0 - recurrence not observed, 1 - recurrence observed). This data is given in files bladerc. cav | dat |xlsx. Data are given in WinBUGS format bladderBUGS . cav| dat |x1sx. The starter file bladderco. odc contains data and also initial values for parameters and censored observations. Students should understand that these formats are equivalent, and be able to convert one into the other as needed. Assume that observed times are exponentially distributed with the rate parameter A; depending on the covariate group, as As = exp{Bo + 81 x group,} After Po and 1 are estimated, since the variable group takes values 0 or 1, the means for the placebo and treatment times become Ho = exp { Bo} = exp{ -Bo} 1 exp {Bo + B1} = exp{-Bo - B1}, respectively. The censored data are modeled as exponentials left truncated by the censoring time. Use noninformative priors on So and B1. (a) Is the 90% Credible Set for #1 - #o all positive? (b) What is the posterior probability of hypothesis H : #1 > Ho? (c) Comment on the benefits of the treatment (a paragraph). "Bladder cancer data from M Pagano and K Gauvreau, "Principles of Biostatistics, 2nd Ed. Duxbury 2000. Chapter 21, Exercise 9, page 512

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Elementary Linear Programming With Applications

Authors: Bernard Kolman, Robert E Beck

2nd Edition

0080530796, 9780080530796

More Books

Students also viewed these Mathematics questions

Question

4. What means will you use to achieve these values?

Answered: 1 week ago