2 Cases Presented: Diagnosis for both Depression

1) African American female (37 years old) presenting with depression. The client is a Christian. The client is married and unable to conceive a child after 7 years of trying. The client is becoming extremely depressed blaming herself for own body's inability to have a child sending her into a spiral of intense negative emotions. In her mind she feels that her husband will leave her due to this misfortune.

2) Hispanic male (14 years old) presenting with depression due to consistent bullying in his school environment. The client is a catholic. The client moved to the United States 2 years ago with his parents and siblings. Due to language barriers the client has had a difficult time making friends. He is currently being bullied at school and recently was suspended from school for fighting when defend himself. The fight was caught on camera making the school environment event worst. The client has been isolating himself to avoid the ridicule of his peers.

Can you please explain Depression according to the DSM-5-TR? Are there any statistics for depression as it relates to these specific populations (African American females in their late 30's and Hispanic males in their late teens)? What are the cultural values about mental health issues regarding depression as it relates to these 2 populations? When these specific clientspresent with depression are there any diagnostics considerations to rule out general medical conditions. Does certain medical conditions rule out the how a clinician diagnoses the client?