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2. Dr. G computed the statistical distribution of scores for S-W alignments between a 1269 aa query sequence and an ensemble of scrambled versions (1000)

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2. Dr. G computed the statistical distribution of scores for S-W alignments between a 1269 aa query sequence and an ensemble of scrambled versions (1000) of a 1246 aa homolog. Fitting of the probability density to the EVD gave Karlin-Altschul parameters K = 0.07958 and 2 =0.3017. A. Using Excel or another application plot the resulting EVD probability density. B. Estimate the most-probable alignment score given these parameters. C. The S-W score for alignment of the query to the unscrambled homolog was 5709 (in the same units). Is this alignment score statistically significant? Estimate its E value

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