2. Twelve separate case-control studies were run to investigate the potential link between presence of a certain genetic trait (the P142 polymorphism of the glycoprotein IIIa subunit of the fibrinogen receptor) and risk of heart attack.' For the jth study, an estimated log-odds ratio, vj, and its (estimated) standard error, oj, were computed: C . It . C . oj oj 1 1.055 0.373 5 1.068 0.471 9 0.507 0.186 2 0.116 -0.025 0.120 10 0.000 0.328 3 0.626 0.229 7 7 -0.117 0.220 11 0.385 0.206 4 0.017 0.117 3 -0.381 0.239 12 0.405 0.254 1 From Burr, et al. (2003), Statistics in Medicine, 22: 1741-1760