23-24. Use the following information to answer the next two questions. You are studying memory in mice and you test 6 SNPs for potential association to a memory QTL. You decide to cross a true-breeding "strong learner" line of mice to a true-breeding "forgetful" line of mice to generate an F1 generation. Then you backcross these F1 individuals to the forgetful parental line to generate a mapping population. In your inbred parental lines, all of the strong learners were homozygous for the G allele at all 6 SNP markers, whereas the forgetful individuals were homozygous for the T allele. You genotype the most forgetful individuals in your mapping population and obtain the following data: 23. What is the estimated map distance between the memory QTL and the closest SNP marker? A. 8.3cM B. 10cm C. 25cm D. 50cm E. These data do not suggest linkage between any of these markers and the memory QTL 24. Which of the following genetic maps is/are possible given the data above (the dash indicates genetic linkage in the specific order given)? Assume that you do NOT already know the chromosomal locations or order of the 6 SNPs. A. 43/5 - memory B. 4 - memory - 3/5 C. 3/54 memory D. B and C E. These data do not suggest linkage between any of these markers and the memory QTL Formulas and 2 table: Table 1. Critical Chi Square Values P(BA)=P(BA)P(A)P=m!(Nm)!N!a(1a)Nmx2=e(ae)2D=p(AB)p(A)p(B)Vx=V+Vep+q=1p1=(1m)p1+mpmp2+2pq+q2=1p0+1=p0(1)H2=Vg+VeVgw=1sf(p)=wA(p2)+wA(2pq)+w(q2)wA(p2)+(0.5)wA(pq)h2=VXVaP(keventsininterval)=ek!t