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3 (6 points) Indicate whether each of the following events are pro-proliferative or anti- proliferative using the drop-down menu: 1 = pro-proliferative, 2 = anti-proliferative

3 (6 points) Indicate whether each of the following events are pro-proliferative or anti- proliferative using the drop-down menu: 1 = pro-proliferative, 2 = anti-proliferative OD V AKT/PKB-mediated inhibition of GSK3 beta RB-mediated recruitment of HDAC to E2F-responsive genes. TGF-beta-mediated up- regulation of p15 WNT-ligand-mediated stabilization of beta-catenin NF-1-mediated RAS- GTPase activity 1. pro-proliferative MYC-mediated degradation 2. anti-proliferative

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