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3 . Homology modeling project using the human GLP - 2 receptor.a . Using the ExPASy server, locate the primary sequence for the human GLP
Homology modeling project using the human GLP receptor.a Using the ExPASy server, locate the primary sequence for the human GLP receptor. Save the sequence as a FASTA file for later use.b Next, using YASARA build a D structural model tertiary structural model for human GLPc After the modeling project is completed, download the predicted structure as a PDB file and answer the following questions.d Which template structures was used in the modeling project?e What is the crystallographic resolution of the template structuresf What is the sequence identity between the template structures and the target structure?g Based on the above answers, do you think your predicted models is trustworthy?h What does model quality evaluation refer toi Name and briefly describe three YASARA methods for model quality evaluation.j Does the YASARA Model Quality analysis suggest that you have at least one good human GLP model? Write a YASARA Macro script that performs the following operations:Open PDB files in YASARA use the iehxxxpdb files from the module crash course in writing macro scriptsUse the AlignMustang command to superimpose of the structures iehpdb to iehpdb onto the reference structure iehpdbPrint the names of the proteins column and RMSDs column to a text file that gets saved in your home directory the same directory where your PDN structures are savedHint: you can modify the superposeligand.mcr file that I uploaded to Module Write your script in the space provided below.
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