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3. In the previous problem, we assumed that we knew each protein conformation corresponded to one unique state. Normally, you do not have this information
3. In the previous problem, we assumed that we knew each protein conformation corresponded to one unique state. Normally, you do not have this information a priori. Let's say that Nopen and Nclosed states exhibit open and closed conformations, respectively. (In other words, the open and closed energy levels have a degeneracy of Nopen and Nclosed, respectively.) A) Find the fraction of time that a protein is in an open conformation, in terms of Nopen,Nclosed,T, and the difference in energies between the two conformations. B) At 300K, the protein is in the open conformation 60% of the time. At 310K, this fraction rises to 65%. Find the difference in energy levels, again in molar units. C) Find the ratio Nopen/Nclosed
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