Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

3. In the survival package, there is a data set called mgus which gives the result of a study of 241 subjects with monoclonal gammapothy

image text in transcribedimage text in transcribed
3. In the survival package, there is a data set called mgus which gives the result of a study of 241 subjects with monoclonal gammapothy of undetermined significance(MGUS). These subjects are at increased risk of developing certain blood diseases. We are interested in using the given covariates: age age of the patient when they were diagnosed, sex male or female, alb albumin level at MGUS diagnosis, creat creatinine level at MGUS diagnosis, hgb hemoglobin concentration at MGUS diagnosis, mspike size of the monoclonal protien spike at MGUS diagnosis.to model the survival time for these patients. We will use futime as our timetofailure measurement and the variable death indicates whether the patient died or was censored. Using a Cox proportional hazards model and likelihood ratio tests, (a) Test the hypothesis that there is a signicant difference between the two sexes. Report a Pvalue and a conclusion. (b) Rerun the test of the difference between the sexes, but use the covariates age, alb, creat , hgb, and mspike to control for differences in the groups. Report a Pvalue and a conclusion. (0) How might we explain the difference in the answers to part (a) and (b)? (d) Propose a set of covariates that you think best ts the fut ime data in a nottoocomplicated way. Justify your choices with regression results

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Negative Binomial Regression

Authors: Joseph M Hilbe

2nd Edition

1139005960, 9781139005968

More Books

Students also viewed these Mathematics questions