3. One set of screening guidelines for the detection of colorectal cancer (CRC) recommends the use of a non-invasive screening test - Fecal Occult Blood Testing (FOBT) - as the initial screen for the disease, and, for those patients with a positive FOBT result, follow up testing with colonoscopy (CS) to presumptively confirm the diagnosis. The most commonly used FOBT in the marketplace has a published sensitivity of 50% and published specificity of 60%. Evidence regarding the efficacy of colonoscopy in detecting CRC varies by location and methodology employed, but is estimated, overall, to have a sensitivity of 95% and specificity of 90%. In the general, average CRC risk population 40 years of age and older, the prevalence of CRC is estimated to be 10%. Assume that you anticipate screening a population of 10,000 patients for CRC each year. On an annual basis: (A) How many actual cases of CRC will FOBT identify by itself? How many actual cases will FOBT miss