40. A missense mutation replaces an alanine residue located in the interior of a soluble protein with a serine residue. What will be the most likely effect of this change on the protein? A) Folding will be disrupted due to the mistaken inclusion of a polar amino acid. B) Folding will be disrupted due to the mistaken inclusion of an unusually bulky amino acid. C) The protein will completely lose its function. D) The protein will be completely unaffected. 41. Which of these statements concerning nucleic acids is / are accurate? I. DNA replication is more accurate than RNA transcription due to the existence of proofreading mechanisms. II. DNA and RNA are equally stable macromolecules. III. Due to the presence of different bases, DNA and RNA strands are unable to bind with one another. IV. The genome of an organism can be entirely composed of either DNA or RNA. A) I only B) I and IV C) II and IV D) I, II, and III 42. DNA is rarely found outside its double-helical form, while RNA is single-stranded and folds on itself to form various structures. RNA's wider structural variety results in: A) RNA having a wider range of functions than DNA. B) RNA being targeted less often for degradation. C) mRNA, tRNA, and rRNA being interchangeable and able to perform similar functions. D) RNA having less stability due to its singlestranded form