5. Answer BOTH parts. Table 1 lists values of pka for three drugs: Table 1. The values of pka for three currently used pharmaceuticals Drug Naproxen 4.2 Acebutolol 9.2 Minocycline 2.8, 9.5 (h) Sketch the graphs depicting the dependence of their solubility versus pH. Explain your reasoning. [60%] (i) Explain the pH-partition hypothesis using the example of pharmaceuticals which are weak bases. [40%]