5. The following plasma drug concentration data has been given to you.

a. Plot this data on both linear-linear and log-linear plots, labeling clearly.

b. Should this model be fitted with a one, two, or three-compartment model? Please justify using residuals/standard error and reason, and plot your final fit along with the original data. Give fit parameters.

c. Tell us more about the drug from the data. Was it most likely oral, or iv injection? Are there different phases, and what would those phases represent?

d. Estimate the initial plasma concentration at t=0, and explain how you got that.

\begin{tabular}{rr} \multicolumn{2}{c}{ [drug] } \\ time(hr) & mg/L \\ 0.2 & 46.1 \\ 0.5 & 40 \\ 1.2 & 31.5 \\ 2.3 & 20.7 \\ 3.2 & 16.3 \\ 4.3 & 12.7 \\ 5 & 11.2 \\ 5.8 & 9.47 \\ 7 & 7.85 \\ 8.9 & 6.29 \\ 9.5 & 6.06 \\ 12 & 4.46 \\ 15 & 3.51 \\ 16 & 3.1 \end{tabular}