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6. Consider a ribosome translating a specific mRNA codon (e.g. UCG) to an amino acid. Compared to a perfect pairing with a tRNA with the
6. Consider a ribosome translating a specific mRNA codon (e.g. UCG) to an amino acid. Compared to a perfect pairing with a tRNA with the correct anticodon (AGC). imagine that a codon-anticodon pairing with one incorrect base pair due to one incorrect anticodon residue is 9 kJ/mol higher in energy, two incorrect base pairs due to two incorrect anticodon residues is 18 kJ/mol higher, and three incorrect base pairs due to three incorrect anticodon residues is 27 kJ/mol higher. tRNA anticodon loop Anticodon 3 AGC 5 UC G 5 Codon 3' mRNA Hint: There are three possible incorrect single-base mismatches in each of the three positions (U, C, or G). a). What is go, the degeneracy of a codon-anticodon pairing with no incorrect base pairs? (2 points) b). What is gi, the degeneracy of a pairing with one incorrect base pair? (2 points) c). What is g2, the degeneracy of a pairing with two incorrect base pairs? (2 points) d). What is g., the degeneracy of a pairing with three incorrect base pairs? (2 points) e). What percent of decoding events occur without mismatches at 280 K? Note the base energy U, cancels in the calculation so you don't need to know its value. Round your answer to 2 decimal places. (Enter 60 if 60%) (5 points)
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