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9) A drug has an apparent volume of distribution (Vd) of 100L and a half-life of 24 hours. The minimum effective concentration of the drug

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9) A drug has an apparent volume of distribution (Vd) of 100L and a half-life of 24 hours. The minimum effective concentration of the drug is 2.0mg/L, and the minimum toxic concentration of the drug is 8.0mg/L. Which of the following dosing regimens would produce and maintain the desired plasma concentration for this drug? A. 1000 mg every 24 hours B. 1000mg first (loading) dose, followed by 500mg every 24 hours C. 600mg every 24 hours D. 600mg first (loading) dose, followed by 300mg every 24 hours E. 300mg every 24 hours

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