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A 44 year old woman has a small number of cancerous polyps along the proximal side of the colon. Her mother was diagnosed with these

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A 44 year old woman has a small number of cancerous polyps along the proximal side of the colon. Her mother was diagnosed with these types of tumors and another sibling has developed gastric cancer. All were identified with cancer in their mid-40s. Analysis of the tumors revealed microsatellite instability; the presence of numerous additional alleles not present in noncancerous cells. Which of the following syndromes best describes this family? familial adenomatous polyposis (FAP) Li-Fraumeni Syndrome HBOC xeroderma pigmentosum A polymorphism is a change in the DNA sequence that... is present at more than 1% in the population results in an altered amino acid sequence has no deleterious effect on the phenotype results in altered gene expression levels The generally deleterious effects caused by inbreeding are due to an increase in... homozygosity of recessive deleterious alleles frequency of deleterious alleles genetic variability mutation rate

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