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A 50-year-old woman is admitted to ICU with urosepsis and severe abdominal pain, requiring intubation for airway protection. She has history of hypertension, and her

A 50-year-old woman is admitted to ICU with urosepsis and severe abdominal pain, requiring intubation for airway protection. She has history of hypertension, and her current BP is 110/80 mm Hg with a heart rate of 112 BPM. Her serum creatinine is 1.6 mg/dL (her creatinine 2 weeks ago was 0.8 mg/dL). She requires fluids. Which one of the following measures of intravascular volume is MOST appropriate for fluid responsiveness?

A. Central venous pressure (CVP)

B. Pulmonary capillary wedge pressure (PCWP)

C. Pulse pressure variation (PPV) and stroke volume variation (SVV)

D. Inferior vena cava diameter

E. Right ventricular end-diastolic volume (RVEDV)

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