A B 1.8- vehicle 120- 1.6- 105- 1.4- -o Asp 2.5 mg/ml 1.2- - Asp 5 mg/ml 90- 1.0- - Asp 10 mg/ml 45-1 # HH Absorbance (OD 570nm) 0.8- Cell viability (% 0.6- 30- 0.4- O 0.2- 15- 0.0 0 24 48 72 Asp - + + + + Treatment time (hr) NAC 0 0 0.5 1 2 (mM) C 100- G2 / M 80- OS O G1 60- Relative cell cycle phase (%) 40- 20- vehicle Asp