a. Explain in detail how to separate a mixture of the following three drugs in water (using solvent extraction). You are provided with: H3PO4, ammonia, hexane and a separation funnel. (5 marks) cosa Ibuprofen (pKa 4.85) diphenhydramine (pKa 8.98) H.C. CH CH Vitamin E b. What would be the peak plasma concentration (Cp) of aspirin in mg/L in the bloodstream of a man weighing 85.5 Kg after he took 2 tablets (720 mg each) orally? Assume the volume of distribution for aspirin is 0.15 L/kg and bioavailability (F) = 45% (4 marks)