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A gene encoding for the PERK receptor in mice has been knocked out or gets a mutation that leads to non-functional. It is known that

A gene encoding for the PERK receptor in mice has been knocked out or gets a mutation that leads to non-functional. It is known that this protein is required to detect misfolded proteins.

  1. What will be the problem during the quality control of protein?
  2. Is there any bypass to recover this problem?

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