A man, apparently in his early 60 s, non-overweight and in good health, comes into your. office complaining of pain in his right eye and reduced clarity of his vision. Upon examination, he shows signs indicating developing glaucoma. You order administration of Acetazolamide to reduce ocular fluid production and lower intraocular pressure. Acetazolamide is a non-competitive inhibitor of carbonic anhydrase and thus will have the following effect on the enzyme: Answers A-E A It will decrease the Vmax. B It will decrease the Km. c It will decrease Vmax and increase Km. D It will increase the Km. E It will increase the Vmax. A young girl (pre-pubescent) presents to the emergency room because of prolonged bleeding after biting her tongue while chewing gum. You order coagulation tests and find the following values: Prothrombin time is 11.7sec (normal=10.0-12.8) and activated partial thromboplastin time 73sec (normal=24.4-33.2). Levels of platelets are normal and the child is not anemic (Hb12.3g/dl, normal=10.5-13.5). You order clotting factors analysis. From the options below, which do you expect may be very low or non-detected? Answers A-E A Factor VII B Factor IX c Factor X D APC complex E Plasmin Refer to the above graph and choose the curve that best represents the statement in each question. Several O2 binding curves are shown above. Curve 3 represents physiological conditions of pH, and CO2 and BPG concentrations, and Curve 1 represents the O2 binding curve for myoglobin. This curve represents a decrease in CO, concentration: Answers A-D A Curve 1 B Curve 2 Curve 3 Curve 4