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A new drug is in development and an appropriate particle size must be found for the appropriate dissolution rate (eg complete dissolution of drug in
A new drug is in development and an appropriate particle size must be found for the appropriate dissolution rate (eg complete dissolution of drug in 30 min). This drug has a continuous water solubility of 10g / mL in a pH range of 1-7. The density of the crystalline form of the drug is given p = 1.52 g / cm3. The diffusion coefficient D = 9 / 10-6 cm2 / sec. Calculate the dissolution times of particles with diameter 1m, 10 m and 100 m.
Hint use the =pr2/2DCs equation. = time for complete dissolution. For good rating solve this correctly. Thank you.
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