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A risk score ranging from 0 to 10 (higher score indicating higher risk) was developed to evaluate risk of catching a viral disease. The AROC

A risk score ranging from 0 to 10 (higher score indicating higher risk) was developed to evaluate risk of catching a viral disease. The AROC (Area under the ROC curve) of the test was 0.88 at a threshold of 7, the sensitivity of the test was 90%, and the specificity of the test was 58%. In the population they tested, the prevalence of the disease was 2%. Which of the following statements are true given this information? (select all correct choices)

A. The researchers evaluated this test in another population where the prevalence of the disease was 10%. We would expect the sensitivity to be higher in this population.

B. To avoid panic, the researchers wanted to avoid false positive results.They chose a good threshold to achieve this.

C. If we apply this test to a group of individuals randomly chosen from those who do not have the disease, 42% of the time the test will report a positive result at the threshold.

D. The researchers would have fewer false positives if the threshold was decreased to 6.

E. If we apply this test to a group of individuals randomly chosen from those who have the disease, 10% of the time the test will report a nagetive result at the threshold.

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