Question: A 23-year-old with asthma has what is described as aspirin sensitivity and experiences severe bronchospasm in response to even small doses of the drug.

A 23-year-old with asthma has what is described as "aspirin sensitivity" and

A 23-year-old with asthma has what is described as "aspirin sensitivity" and experiences severe bronchospasm in response to even small doses of the drug. The most likely explanation for this is that the aspirin a. Induces hypersensitivity of H1 receptors on airway smooth muscles b. Blocks synthesis of endogenous prostaglandins that have bronchodilator activity c. Induces formation of antibodies directed against the salicylate on airway mast cells d. Induces hypersensitivity of muscarinic receptors on airway smooth muscles

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