According to a study, the percentage of patients exhibiting an above-normal temperature response to a specified dose of a histamine can be modeled by a function R(a) that has derivative R'(x) = 100+5 (1+ex+5) where is the natural logarithm of the dose in milimoles (mM). Find a formula for R() and evaluate it at =-5.3. Remember: To determine the value of the constant of integration, use the fact that R(a) 0 as . Round your answer to three decimal places. *K.A. Skau, "Teaching Pharmacodynamics: An Introductory Module on Learning Dose-Response Relationships," American Journal of Pharmaceutical Education 68 (2004), article 73.