advance physics

Po Ap G Figure 2.6 Linear model of respiratory Question: mechanics. Using the SIMULINK program, incorporate into the respiratory mechanic's model d' Pao 1 dPao = Rc di di2 RPCT dt (Cs + RP CT) at + RPCs (C e (2.16) where CT is defined by CT = (2.17) Assume the value of the various pulmonary parameters are as follows: Rc = 1 cm H2OsL-1, Rp = 0.5 cm H2OsL-', CL = 0.2Lem H20-1, Cw = 0.2Lem H20-1, and Cs = 0.005 L cm H20-1 (a) Through model simulations (Simulink) , determine how airflow and tidal volume would vary in response to sinusoidal pressure waveforms at the airway opening (Pao) applied at 15 and at 60 breaths min-. With amplitude of 2.5 cm H20. (This part is already done in the book at page 33 and 34) (b) To simulate a subject with emphysema, increase lung compliance (CL to 0.4 Lem H20 and peripheral airway resistance (Rp) to 7 cm H20 s L-'. Determine how airflow and tidal volume would vary in response to sinusoidal pressure waveforms at the airway opening (Pao) applied at 15 and at 60 breaths min-. With amplitude of 2.5 cm H20. Compare the frequency dependence of the resulting airflow and volume waveforms to those obtained for the normal subject. Hints: - Read section 2.9 COMPUTER ANALYSIS AND SIMULATION-MATLAB AND SIMULINK in page 30 in PHYSIOLOGICAL CONTROL SYSTEMS book Find Q(s)/Pao(S) To find frequency in radians/sec = 2* n ( breaths min-'/60)