Question
An anti-inflammatory drug, MW=357.79) is to be delivered by a surgically implanted drug-delivery device in which the drug inside a membrane reservoir transfers through the
An anti-inflammatory drug, MW=357.79) is to be delivered by a surgically implanted drug-delivery device in which the drug inside a membrane reservoir transfers through the membrane to the surrounding fluid and tissue. The outside surface area of the reservoir is A (cm2). Furthermore, the concentration of the drug on the outside surface of the reservoir is CR (gmol/L), but the concentration a few centimeters from the reservoir can be assumed to equal 0. The fluid outside the reservoir is flowing slowly, which aids the transfer, and the mass-transfer coefficient is hm (cm/s). What is the amount of drug (mg) that will be delivered in t minutes? by taking, 295.12 g/g.mol, 0.000054 g.mol/L, 0.091 cm/s, 4.2cmsquare, 3 minutes
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