Answered step by step
Verified Expert Solution
Question
1 Approved Answer
Answer ALL parts a) - c). The following transformation was accomplished using a lipase enzyme in organic solvent. 1 Thermomyces lanuginosus hexane 22 88% yield,
Answer ALL parts a) - c). The following transformation was accomplished using a lipase enzyme in organic solvent. 1 Thermomyces lanuginosus hexane 22 88% yield, 92% e.e. a) Draw a curly arrow mechanism for the enzyme-catalysed transformation of 1 to 3. You must include the participation of all key active site amino acid residues. [6 b) Why is vinyl acetate (2) used as the acyl donor here, as opposed to the much more inexpensive acetic acid (ethanoic acid, CH3CO2H )? Illustrate your answer with diagram(s). [6 Answer ALL parts a) - c). The following transformation was accomplished using a lipase enzyme in organic solvent. 1 Thermomyces lanuginosus hexane 22 88% yield, 92% e.e. a) Draw a curly arrow mechanism for the enzyme-catalysed transformation of 1 to 3. You must include the participation of all key active site amino acid residues. [6 b) Why is vinyl acetate (2) used as the acyl donor here, as opposed to the much more inexpensive acetic acid (ethanoic acid, CH3CO2H )? Illustrate your answer with diagram(s). [6
Step by Step Solution
There are 3 Steps involved in it
Step: 1
Get Instant Access to Expert-Tailored Solutions
See step-by-step solutions with expert insights and AI powered tools for academic success
Step: 2
Step: 3
Ace Your Homework with AI
Get the answers you need in no time with our AI-driven, step-by-step assistance
Get Started