Assignment 1 (12%) This assignment has 8 questions for a total of 100 marks and counts 12% towards your final course grade. 1. Chapter 1: (12 marks) For the study summarized in the abstract below: a. Identify the "5 W's plus H." b. Name each variable and identify whether it is categorical or quantitative. For each quantitative variable identify the units used. Hypertens, 2007 Jan;25(1):227-34 The effect of vitamin E on blood pressure in individuals with type 2 diabetes Ward NC. Wu JH. Clarke MW, Puddey IB, Burke V, Croft KD, Hodgson JM. School of Medicine and Pharmacology, University of Westem Australia, Perth, Australia department of Core Clinical Pathology and Biochemistry, Royal Perth Hospital, Perth, Australia OBJECTIVE: Oxidative stress has been suggested to play a role in the development of diabetes, Typertension and vascular dysfunction. Vitamin E, a major lipid-soluble dietary antioxidant, has two major dietary forms, alpha-tocopherol and gamma-tocopherol. The potential importance of gamma-tocopherol has argely been overlooked. Our aim was to investigate the effect of alpha-tocopherol and gamma-tocopherol upplementation on 24-h ambulatory blood pressure (BP) and heart rate, vascular function and oxidative stress in individuals with type 2 diabetes METHOD: Fifty eight individuals with type 2 diabetes were randomized in a double-blind, placebo controlled trial. Participants were randomized to a daily dose of 500 mg/day KRK-alpha-tocopherol, 500 mg/day mixed tocopherols or placebo for 6 weeks. RESULTS. Treatment with alpha-tocopherol significantly increased systolic BP [7.0 (5.2. 8.8) mmHg, Pc 0.0001j. diastolic BP (53 (4.0. 6.5) mmlig, P .0.0001). pulse pressure [1.8 (0.n. 30) mmlig. P