Question
Calculate the solubility, in both mol/L and g/100 mL, of the following drugs at the given pH value. (a) Papaverine at pH = 4.8, a
Calculate the solubility, in both mol/L and g/100 mL, of the following drugs at the given pH value.
(a) Papaverine at pH = 4.8, a basic drug, S(0) = 1.7x10^-4 g/100 mL water; pKa = 8.07
(b) Aspirin at pH 5.1, S(0) = 1g/300 mL water; pKa = 3.5
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Biochemistry
Authors: Mary K. Campbell, Shawn O. Farrell
8th edition
9781305176621, 1285429109, 1305176626, 978-1285429106
