Can anyone help me with these 3 questions by mintab? Thank you.

1. In the early part of this century, the drug company, Merck, produced a powerful non steroidal anti-inflammatory drug (NSAID) known as Vioxx. Vioxx was very effective in reducing pain due to arthritis and, unlike some NSAIDs, did not cause digestive system or liver problems. However, a couple of years after Vioxx was introduced to the market, some independent studies showed a possible connection between NSAIDs and increased risk of heart attack in the elderly. Since many arthritis sufferers (and many Vioxx users) are elderly, these studies were a cause of concern. To test whether this was the case for Vioxx, Merck conducted a large-scale study in which 3118 randomly selected elderly Vioxx users were put on the drug while 2870 were given a placebo. The volunteers were monitored for 18 months. During this time, 348 of the Vioxx group members and 276 members of the placebo group suffered heart attacks. a. Compute by hand a 90% confidence interval for the difference in heart attack risk between Vioxx users and non-Vioxx users (the placebo group.) Confirm your interval with Minitab. (Stat->Basic Statistics->2-Proportion: Summarized data; Enter parameters ->Options: Confidence level: 90->OK -> OK) b. Interpret the interval. What action does it suggest should be taken regarding Vioxx?v