Can you compare these sequences with a reference sequence to identify a mutation that may cause resistance to treatment in a cancer patient and explain the result to me$?($Seq$1)$

TCTTTCCTGTATGGAAATCCAGTTATTCTGTCTCCACTTGTTGAAATAGGCTTCCTTTCTCTACTGAATGCTTTTAATTTTAATTATTTTACAGTTGGAGTATAGGGCTACCATTTTAGTGCTATTTTCTTATTTTCTTTGTTAATTTTT

$$

$($Seq$2)$

GGCGAGGGTCTGACGGGTAGAGTGTGCGTGGCTCTCACCACCCGCACGTCTGTAGGGAAGTACATCAAGACCTGGCGGCCACGCTACTTCCTCCTCAAGAATGATGGCACCTTCATTGGCTACAAGGAGCGGCCGCAGGATGTGGACCAA

$$

$($Seq$3)$

ATCCCCTCAGCCCCCTGCTGTCTGTTCCCTCTGCCTGCAGAATGCCAGCTGATGAAGACCGAGAGGCCGCGACCCAACACCTTTGTCATACGCTGCCTGCAGGCGACCACAGTCATCGAGAGGACCTTCCACGTGGATTCTCCAGACGAG

$$

$($Seq$4)$

AAAGAGCTTCCAAAACTGCTTAAGCTTTGACTGCACAAAACCTGCATCACCTCCAGTTGAGAAACTCAAGAGAATAAGTAAGTTATGGAGTTGGAGACCCCAGCTTAACTACTAGCTTTAAAATAGTGAAATCAACATTTTCAAATCTAT

$$

$($Seq$5)$

CAGGAATGGGCACAGCAGCCTTGGGAGGTGCAGACCTCAGTGATCAACCCTAAATGCTGATGCCCCAGGGCAGATGCCATCAGTGGACTTCCTGGGTTGTGACACCTGTTTCTTCGAATCAGAGAAACCCTGGCTCCGGAGAGAAATTGG