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Can you explain how to solve the portfolio variance of Portfolio Healthcare Fund/Inverse ETF and Portfolio Healthcare Fund/Biotech Fund? I have been able to solve

Can you explain how to solve the portfolio variance of Portfolio Healthcare Fund/Inverse ETF and Portfolio Healthcare Fund/Biotech Fund? I have been able to solve everything prior to this, including the E(R) of both Portfolios,  but I'm stuck at this point. 

Expected return [E(R)] Variance (Var) Portfolio Healthcare Fund / Inverse ETF Portfolio Healthcare Fund / Biotech Fund 11.2% 14.0% 0.08% 2.24% Standard deviation (SD) 2.9% 15.0% Coefficient of variation (CV) 0.26 1.07 Correlation coefficient -0.870 0.993

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