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Case-Control The following table shows data collected from a cohort study of the effect of sex on a disease, stratified by age group. The investigators

Case-Control The following table shows data collected from a cohort study of the effect of sex on a disease, stratified by age group. The investigators intend to nest a case-control study in the cohort study, using all of the cases and the same number of controls. Several designs for control selection have been proposed. For each design, estimate the number of controls that would be expected to fall into each combination of age and sex. Round the number of expected controls in each combination to the nearest integer. For each design, estimate the Pooled OR from the case-control study and write the name of the relative effect that the OR estimates. Old Young Male Female Male Female Cases 400 100 100 100 non-cases 1600 900 900 1900 Persons 2000 1000 1000 2000 person-years 8800 4700 4700 9700

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