Cell membrane receptors need to protrude above the cell's glycocalix so the ligands (like hormones) can reach the receptors. How does nature solve this glycocalix inpediment? All of them O By creating pores in the glycocalix through which the protein goes through By creating long alpha helices to extend the receptor above the glycocalix By attaching negatively charged clycosaminglycans to the glycocalix portion of the receptor