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Consider a cell composed of a cell body to which is attached a long, thin, tubular process ( e . g . , the axon
Consider a cell composed of a cell body to which is attached a long, thin, tubular "process" eg the axon of a neuron or the flagellum of a sperm cell of length l cm Figure on right Suppose some substance n eg a metabolite is generated in the cell body and diffuses along the process, all along which the substance is consumed at a constant uniform rate, alpha n mols per unit length. The continuity equation for the substance thus becomes cn t Phi n x alpha n A where A is the assumed constant crosssectional area of the process. a Combine the modified continuity equation given above with Ficks law to obtain a modified form of the diffusion equation that must be satisfied by cn b Show that a solution of this equation in the steady state cn t Phi n t is cn x alpha n DA x ax b and find values of the constants a and b corresponding to the boundary conditions cn o C and Phi n l Consider a cell composed of a cell body to which is attached a long, thin, tubular "process" eg the axon of a neuron or the flagellum of a sperm cell of length lcm Figure on right Suppose some substance n eg a metabolite is generated in the cell body and diffuses along the process, all along which the substance is consumed at a constant uniform rate, alpha nmols per unit length. The continuity equation for the substance thus becomes delcndeltdelPhi ndelxalpha nA where A is the assumed constant crosssectional area of the process. a Combine the modified continuity equation given above with Fick's law to obtain a modified form of the diffusion equation that must be satisfied by cn process b Show that a solution of this equation in the steady state delcndeltdelPhi ndelt is cnxalpha nDAxaxb and find values of the constants a and b corresponding to the boundary conditions cnoC and Phi nl
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