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Consider a cell composed of a cell body to which is attached a long, thin, tubular process ( e . g . , the axon

Consider a cell composed of a cell body to which is attached a long, thin, tubular "process" (e.g., the axon of a neuron or the flagellum of a sperm cell) of length l cm (Figure on right). Suppose some substance n (e.g., a metabolite) is generated in the cell body and diffuses along the process, all along which the substance is consumed at a constant uniform rate, \alpha n mol/s per unit length. The continuity equation for the substance thus becomes cn t =\Phi n x \alpha n A , where A is the (assumed constant) cross-sectional area of the process. a. Combine the modified continuity equation given above with Ficks law to obtain a modified form of the diffusion equation that must be satisfied by cn. b. Show that a solution of this equation in the steady state (cn t =\Phi n t =0) is cn x =\alpha n 2DA x 2+ a0x + b0 and find values of the constants a0 and b0 corresponding to the boundary conditions cn o = C0 and \Phi n l =09_1 Consider a cell composed of a cell body to which is attached a long, thin, tubular "process" (e.g., the axon of a neuron or the flagellum of a sperm cell) of length lcm (Figure on right). Suppose some substance n (e.g., a metabolite) is generated in the cell body and diffuses along the process, all along which the substance is consumed at a constant uniform rate, \alpha _(n)mo(l)/(s) per unit length. The continuity equation for the substance thus becomes (delc_(n))/(delt)=-(del\Phi _(n))/(delx)-(\alpha _(n))/(A), where A is the (assumed constant) cross-sectional area of the process. a. Combine the modified continuity equation given above with Fick's law to obtain a modified form of the diffusion equation that must be satisfied by c_(n). process b. Show that a solution of this equation in the steady state ((delc_(n))/(delt)=(del\Phi _(n))/(delt)=0) is c_(n)(x)=(\alpha _(n))/(2DA)x^(2)+a_(0)x+b_(0) and find values of the constants a_(0) and b_(0) corresponding to the boundary conditions c_(n)(o)=C_(0) and \Phi _(n)(l)=0.

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