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Consider a composite matrix which is comprised of two phases: Chondrocytes and a viscous matrix of extra cellular fluid (ECF). The chondrocytes cells occupy 60
Consider a composite matrix which is comprised of two phases: Chondrocytes and a viscous matrix of extra cellular fluid (ECF). The chondrocytes cells occupy 60 percent of the overall matrix volume and the plasma occupies 40 percent. Estimate the overall effective diffusivity coefficient for a solute with diameter 0.20nm through the composite matrix at 37C. Chondrocytes are permeable. You can assume that these nanostructures have a pore size 3.5nm. and a porosity of 35 percent and the ECF is a homogeneous fluid with viscosity 3.5cp. The diffusion coefficient in the chondrocytes is 4.2106cm2/sec
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