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1. What gametes would the following genotypes produce? a. AaBb (no linkage) b. AbifaB (complete linkage) c. AB//ab (incomplete linkage) 2. Assume that in

  

1. What gametes would the following genotypes produce? a. AaBb (no linkage) b. AbifaB (complete linkage) c. AB//ab (incomplete linkage) 2. Assume that in humans free ear lobes (D) and attached (d) and freckles (F) and no freckles (f) are linked to chromosome 10. Matings between DdFf and ddff people produce the following offspring: 220 free ear lobes, freckles 190 attached ear lobes, no freckles 35 45 500 What is the distance between D(d) and F(f)? If D and F were 20 CM apart, what gametes would a DdFf person produce? 3. Define/Describe/etc: a. FISH b. aneuploidy c. trisomy d. metacentric e. acrocentric f. Albert Blakeslee free ear lobes, no freckles attached ear lobes, freckles g. Calvin Bridges h. Langdon Down i. Turner's Syndrome 4. What would be a human example of a. aneuploidy (2n + 1) b. aneuploidy (2n-1) 5. What is the effect of the mother's age on aneuploidy? 6. With diagrams, show how nondisjunction can lead to tisomy 7. What may be an explanation of why Turner's syndrome females are sterile although human females have one X chromosome inactivated? 8. What may be an explanation of why Klinefelter's syndrome males are not normal although one X chromosome inactivated? 9. How can mitotic nondisjunction lead to mosaicism? 10. How can auto and allotetraploids form? 11. Why are triploids sterile? 12. With a human examples, discuss how duplication, inversion and translocation can be evolutionary forces. 13. What is meant by 46, XX del5p(15.2)?

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