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Cystic fibrosis can be caused by a mutation in the CFTR gene, which encodes for a plasma membrane ion transporter. Briefly explain why a mutation

Cystic fibrosis can be caused by a mutation in the CFTR gene, which encodes for a plasma membrane ion transporter. Briefly explain why a mutation in the DNA sequence encoding the first 20 amino acids could lead to defective ion activity by the cell inducing the disease?

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