Sickle-cell anemia is caused by a mutation in one of the codons in the gene for -globin;

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Sickle-cell anemia is caused by a mutation in one of the codons in the gene for β-globin; because of this mutation, the sixth amino acid in the β-globin polypeptide is a valine instead of a glutamic acid. A less severe type of anemia is caused by a mutation that changes this same codon to one specifying lysine as the sixth amino acid in the β-globin polypeptide. What word is used to describe the two mutant forms of this gene? Do you think that an individual carrying these two mutant forms of the β-globin gene would suffer from anemia? Explain.

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Principles of Genetics

ISBN: 978-1119142287

7th edition

Authors: D. Peter Snustad, Michael J. Simmons

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