Decarboxylation of glyoxalate $($S$)$ by mitochondria is inhibited by malonate $($I$).$ Using the

following data obtained in batch experiments, determine the following:

Glyox,S $($mM$)$ Rate of CO$2$ evolution, v $($mmoles$/$l$-$h$)$

I $=0$ I $=1\mathrm{.}26$ mM I $=1\mathrm{.}95$ mM

$0\mathrm{.}251\mathrm{.}020\mathrm{.}730\mathrm{.}56$

$0\mathrm{.}331\mathrm{.}390\mathrm{.}870\mathrm{.}75$

$0\mathrm{.}401\mathrm{.}671\mathrm{.}090\mathrm{.}85$

$0\mathrm{.}501\mathrm{.}891\mathrm{.}301\mathrm{.}00$

$0\mathrm{.}602\mathrm{.}081\mathrm{.}411\mathrm{.}28$

$0\mathrm{.}752\mathrm{.}441\mathrm{.}821\mathrm{.}39$

$1\mathrm{.}002\mathrm{.}502\mathrm{.}171\mathrm{.}82$

a$.$ What type of inhibition is this?

b$.$ Determine the constants Vm$,$ Km$,$ and KI$.$