Description of Assignment: 

Task 1: In class test (AC1.1, 1.2, 1.3):

The 1-hour test will take place on May 26^th at 1.30. Read through the assessment criteria so that you understand what you need to revise. You will be asked to produce Punnett squares as part of the test. The test conditions can be found on the following page.

Task 2 (AC2.1):

Use flowcharts to depict the phases of meiosis and mitosis, focusing on the movement of chromosomes. Hand drawn images should be included. Provide a typed justification of why certain chromosome movement events are important. (500 words maximum).

Task 3 (AC2.2, 2.3):

(500 words maximum):

Gene and chromosome mutations are two types of alterations that occur in the genome of an organism. Explain what is meant by mutation and discuss the difference between these two forms (AC 2.2).

Explain the causes of DNA mutation in a human being, and how risk of mutation can be reduced (AC 2.3).

Task 4 (AC3.1):

You work for a genetics counselling service and have been asked to write a letter to a 25-year-old woman who has been referred for genetics testing by her GP. She has expressed concerns that she may have genetic mutations linked to two genetic diseases.

In your letter, choose two genetic diseases and explain how they can be managed by the individual and the NHS/government policy. How can this disease be prevented? (350 words maximum). As you are writing to a patient, assume that she is not a science specialist.

The genetic diseases you can choose are sickle cell anaemia; Huntingdon’s disease; Duchenne Muscular Dystrophy; Tay-Sachs Disease; Haemophilia; Cystic Fibrosis; Lesch-Nyhan Syndrome

Across tasks 2-4:

• Where you use information or facts from a source such as a textbook or website, ensure that your work is referenced in the text, and you include a bibliography. You should follow the Harvard referencing system.
• Ensure that you read the grade guidance below so that you know what is required to achieve a Merit or Distinction.

Test rules and procedures

• Arrive for the test early. If you arrive after the test has started, you will not be permitted to enter the test room as it would disturb your fellow students. 
• Mobile telephones must be switched off and placed out of reach.
• You will be provided with a question-and-answer booklet. 
• You are permitted to use some pens, pencils, a ruler, and a rubber. You may have a bottle of water on your desk.
• All your other personal belongings need to be left at the front of the room away from the desks. You are not permitted to bring any notes into the test.
• Once the test has started you must not communicate with anyone except the invigilator. If you need to communicate with the invigilator, you should raise your hand and wait for her/him to come to you.
• You need permission from the invigilator to leave the test room (e.g., to go to the toilet). If you leave the room, then you may not take the question paper or your answer booklet with you. If you leave without permission, then you will not be permitted to re-enter the test.
• You should not leave your desk until all your papers/scripts have been collected. You should not speak to your peers until you have left the test room.
• Any learners found to have broken the rules of test will have their scripts automatically invalidated. This means that you will have to undertake a resubmission test.

Preparing for the test

• Make sure that you have read the assessment criteria and grade guidance so that you know what to revise and what is expected from your answers.
• If you normally need to be contactable by phone, ensure that those who may contact you are aware of the times that you will be in the test and will not have access to your phone.
• If you require special conditions for sitting tests (e.g., extra time), inform your tutor so that they can confirm whether you are eligible for these accommodations and make appropriate arrangements.